![]() ![]() Using a repeated-measures design, we randomly assigned 38 subjects to receive two combinations of injections at two separate appointments. (2/33)To determine whether a repeated intraosseous (IO) injection would increase or prolong pulpal anesthesia, we measured the degree of anesthesia obtained by a repeated IO injection given 30 min following a combination inferior alveolar nerve block/intraosseous injection (IAN/IO) in mandibular second premolars and in first and second molars. ( +info)Īnesthetic efficacy of a repeated intraosseous injection given 30 min following an inferior alveolar nerve block/intraosseous injection. ![]() We question the philosophy of administering these drugs for change in pain threshold at the levels used here preoperatively. No elevation of the pain threshold occurred with narcotic drugs or with nonsteroidal anti-inflammatory drugs: our research shows that the electric pulp tests of patients who have taken these drugs preoperatively will have results similar to those of patients who have taken no drugs. Clinically, however, the superiority of acetaminophen is questionable. ![]() Acetaminophen elevated the pain threshold statistically significantly. The change in pain threshold was measured by electric pulp testing. (1/33)The purpose of this study was to compare changes in pain threshold caused by meperidine, naproxen sodium, acetaminophen, and placebo. Change in pain threshold by meperidine, naproxen sodium, and acetaminophen as determined by electric pulp testing.
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